@article{JSS4085,
author = {Vignesh K. Alamanda and Myra M. Robinson and Jeffrey S. Kneisl and Joshua C. Patt},
title = {Functional and survival outcomes in patients undergoing surgical treatment for metastatic disease of the spine},
journal = {Journal of Spine Surgery},
volume = {4},
number = {1},
year = {2018},
keywords = {},
abstract = {Background: Retrospective review of a prospective database. Spine metastasis has been shown to occur in 40% of cancer patients with an annual incidence of over 18,000 cases in North America alone. In this study, we sought to explore the functional and survival outcomes of patients undergoing surgical treatment for metastatic disease of the spine.
Methods: A retrospective cohort study of a prospective database at a major cancer center was conducted. A total of 55 patients who met the inclusion criteria from January 2010 to December 2015 were included. Functional status was assessed through patient’s ambulatory status. Patient and tumor characteristics were analyzed and regression analyses were performed.
Results: Renal cell carcinoma (RCC) was the most common subtype encountered (27.3%). Excluding patients who had spinal metastasis at time of diagnosis, the median time to spinal metastasis from cancer diagnosis was 2.5 years. Median overall survival (OS) time was 1.8 years post diagnosis and 1.6 years post-surgical intervention. Age and tumor subtype were independent predictors of death (P},
issn = {2414-4630}, url = {https://jss.amegroups.org/article/view/4085}
}