How to cite item

Limited morbidity and possible radiographic benefit of C2 vs. subaxial cervical upper-most instrumented vertebrae

   
@article{JSS4581,
	author = {Peter G. Passias and Cole A. Bortz and Frank Segreto and Samantha Horn and Katherine E. Pierce and Haddy Alas and Avery E. Brown and Renaud Lafage and Virginie Lafage and Justin S. Smith and Breton Line and Robert Eastlack and Daniel M. Sciubba and Eric O. Klineberg and Alexandra Soroceanu and Douglas C. Burton and Frank J. Schwab and Shay Bess and Christopher I. Shaffrey and Christopher P. Ames and on behalf of the International Spine Study Group (ISSG)},
	title = {Limited morbidity and possible radiographic benefit of C2 vs. subaxial cervical upper-most instrumented vertebrae},
	journal = {Journal of Spine Surgery},
	volume = {5},
	number = {2},
	year = {2019},
	keywords = {},
	abstract = {Background: The study aims to evaluate differences in alignment and clinical outcomes between surgical cervical deformity (CD) patients with a subaxial upper-most instrumented vertebra (UIV) and patients with a UIV at C2. Use of CD-corrective instrumentation in the subaxial cervical spine is considered risky due to narrow subaxial pedicles and vertebral artery anatomy. While C2 fixation provides increased stability, the literature lacks guidelines indicating extension of CD-corrective fusion from the subaxial spine to C2.
Methods: Included: operative CD patients with baseline (BL) and 1-year postop (1Y) radiographic data, cervical UIV ≥ C2. Patients were grouped by UIV: C2 or subaxial (C3-C7) and propensity score matched (PSM) for BL cSVA. Mean comparison tests assessed differences in BL and 1Y patient-related, radiographic, and surgical data between UIV groups, and BL-1Y changes in alignment and clinical outcomes.
Results: Following PSM, 31 C2 UIV and 31 subaxial UIV patients undergoing CD-corrective surgery were included. Groups did not differ in BL comorbidity burden (P=0.175) or cSVA (P=0.401). C2 patients were older (64 vs. 58 yrs, P=0.010) and had longer fusions (9 vs. 6 levels, P=0.002). Overall, patients showed BL-1Y improvements in TS-CL (P},
	issn = {2414-4630},	url = {https://jss.amegroups.org/article/view/4581}
}